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Side Effects

Like other medicines, LYRICA® (pregabalin) capsules CV may cause side effects, especially when you start treatment.

LYRICA may cause serious, even life-threatening, allergic reactions. Stop taking LYRICA and call your doctor right away if you have any of these signs of a serious allergic reaction:

  • Swelling of your face, mouth, lips, gums, tongue, or neck
  • Trouble breathing
  • Rash, hives (raised bumps), or blisters

Like other antiepileptic drugs, LYRICA may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call a health care provider right away if you have new or worsening depression, suicidal thoughts or actions, or unusual changes in mood or behavior.

LYRICA may cause swelling of your hands, legs, and feet. This swelling can be serious for people with heart problems.

LYRICA may cause dizziness and sleepiness. Do not drive a car, work with machines, or do other dangerous activities until you know how LYRICA affects you. Ask your health care provider about when it will be okay to do these activities.

LYRICA may cause problems with your eyesight, including blurry vision.

The most common side effects are:

  • Dizziness
  • Blurry vision
  • Weight gain
  • Sleepiness
  • Trouble concentrating
  • Swelling of hands and feet
  • Dry mouth
  • Feeling "high"

For a complete list of side effects, see the Medication Guide for LYRICA.

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Learn What to Expect From LYRICA

Enroll in Stepping Forward from Diabetic Nerve PainTM, a free e-mail program that gives you valuable information about what to expect from your LYRICA treatment. The program also provides support to help you keep on course with LYRICA and take control of your pain. And you’ll receive important articles on health and wellness from experts at the Mayo Clinic.